New insights into the variable effectiveness of levothyroxine monotherapy for hypothyroidism

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Current evidence for the treatment of hypothyroidism with levothyroxine/levotriiodothyronine combination therapy versus levothyroxine monotherapy

OBJECTIVE Hypothyroidism is relatively common, occurring in approximately 5% of the general US population aged ≥12 years. Levothyroxine (LT4) monotherapy is the standard of care. Approximately, 5%-10% of patients who normalise thyroid-stimulating hormone levels with LT4 monotherapy may have persistent symptoms that patients and clinicians may attribute to hypothyroidism. A long-standing debate ...

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ژورنال

عنوان ژورنال: The Lancet Diabetes & Endocrinology

سال: 2015

ISSN: 2213-8587

DOI: 10.1016/s2213-8587(15)00325-3